| Bioactivity | (R)-BAY-85-8501 is the less active Enantiomer of BAY-85-8501. BAY-85-8501 is a selective and potent inhibitor of Human Neutrophil Elastase (HNE), with an IC50 of 65 pM[1]. | ||||||||||||
| Name | (R)-BAY-85-8501 | ||||||||||||
| CAS | 2446175-39-7 | ||||||||||||
| Formula | C22H17F3N4O3S | ||||||||||||
| Molar Mass | 474.46 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
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| Reference | [1]. Von Nussbaum F, et al. Freezing the Bioactive Conformation to Boost Potency: The Identification of BAY 85-8501, a Selective and Potent Inhibitor of Human Neutrophil Elastase for Pulmonary Diseases. ChemMedChem. 2015 Jul;10(7):1163-73. |
(R)-BAY-85-8501
CAS: 2446175-39-7 F: C22H17F3N4O3S W: 474.46
(R)-BAY-85-8501 is the less active Enantiomer of BAY-85-8501. BAY-85-8501 is a selective and potent inhibitor of Human N
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