Bioactivity | (R)-Avanafil ((R)-TA1790) is a selective PDE5 inhibitor (IC50: 5.2 nM). (R)-Avanafil can be used for research of erectile dysfunction[1]. |
Target | 5.2 nM (PDE5). |
Name | (R)-Avanafil |
CAS | 1638497-26-3 |
Formula | C23H26ClN7O3 |
Molar Mass | 483.95 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Sakamoto T, et al. The discovery of avanafil for the treatment of erectile dysfunction: a novel pyrimidine-5-carboxamide derivative as a potent and highly selective phosphodiesterase 5 inhibitor. Bioorg Med Chem Lett. 2014 Dec 1;24(23):5460-5. |