| Bioactivity | (R)-(+)-Dimethindene maleate is an orally active H1-receptor blocker with antihistaminic properties in pigs[1]. |
| Invitro | (R)-(+)-Dimethindene maleate possesses membrane-stabilising effect[1]. |
| In Vivo | (R)-(+)-Dimethindene maleate (10 mL/kg; i.g.; once) shows antihistaminic activity with an ED50 of 2.73 mg/kg in pigs[1]. Animal Model: |
| Name | (R)-(+)-Dimethindene maleate |
| CAS | 136152-64-2 |
| Formula | C24H28N2O4 |
| Molar Mass | 408.49 |
| Appearance | Solid |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | 4°C, stored under nitrogen, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture) |
| Reference | [1]. Leuschner J, et al. Evaluation of the dose-effect curves of dimethindene maleate enantiomers in various animal models. Agents and Actions, 1992, 36(2): C431-C433. |
(R)-(+)-Dimethindene maleate
CAS: 136152-64-2 F: C24H28N2O4 W: 408.49
(R)-(+)-Dimethindene maleate is an orally active H1-receptor blocker with antihistaminic properties in pigs.
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