| Bioactivity | (E/Z)-Teriflunomide ((E/Z)-A77 1726) is the active metabolite of Leflunomide (HY-B0083). Leflunomide is an immunomodulatory agent that may exert effects by inhibiting the mitochondrial enzyme dihydroorotate dehydrogenase (DHODH). Leflunomide can be used for the research of rheumatoid arthritis (RA)[1]. | ||||||||||||
| Name | (E/Z)-Teriflunomide | ||||||||||||
| CAS | 108605-62-5 | ||||||||||||
| Formula | C12H9F3N2O2 | ||||||||||||
| Molar Mass | 270.21 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
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| Reference | [1]. R I Fox, et al. Mechanism of action for leflunomide in rheumatoid arthritis. Clin Immunol. 1999 Dec;93(3):198-208. |
(E/Z)-Teriflunomide
CAS: 108605-62-5 F: C12H9F3N2O2 W: 270.21
(E/Z)-Teriflunomide ((E/Z)-A77 1726) is the active metabolite ofLeflunomide(HY-B0083). Leflunomide is an immunomodulator
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