| Bioactivity | (E/Z)-SIB-1893 is a racemic compound of (E)-SIB-1893 and (Z)-SIB-1893 isomers. (E)-SIB-1893 is a selective non-competitive metabotropic glutamate subtype 5 receptor (mGluR5) antagonist[1]. |
| In Vivo | (E)-SIB-1893 produces hypothermia in freely moving rats in a dose-dependent manner[1]. |
| Name | (E/Z)-SIB-1893 |
| CAS | 6266-99-5 |
| Formula | C14H13N |
| Molar Mass | 195.26 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Łuszczki JJ, et al. Non-competitive metabotropic glutamate subtype 5 receptor antagonist (SIB-1893) decreases body temperature in rats. Pharmacol Rep. 2005;57(6):795-801. |
(E/Z)-SIB-1893
CAS: 6266-99-5 F: C14H13N W: 195.26
(E/Z)-SIB-1893 is a racemic compound of (E)-SIB-1893 and (Z)-SIB-1893 isomers. (E)-SIB-1893 is a selective non-competiti
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