Bioactivity | Rigosertib (ON-01910) is a biochemical reagent that can be used as a biological material or organic compound for life science related research. |
Invitro | Rigosertib (ON-01910) sodium 是一种非 ATP 竞争性 PLK1 抑制剂,IC50 为 9 nM,比 Plk2 选择性高 30 倍,对 Plk3 没有抑制活性。 |
Name | (E/Z)-Rigosertib sodium |
CAS | 1225497-78-8 |
Formula | C21H24NNaO8S |
Molar Mass | 473.47 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Gumireddy K, et al. ON01910, a non-ATP-competitive small molecule inhibitor of Plk1, is a potent anticancer agent. Cancer Cell. 2005 Mar;7(3):275-86. |