(E/Z)-IT-603_product_DataBase

CAS: 292168-90-2 F: C11H9BrN2O3S W: 329.17

(E/Z)-IT-603 is a mixture of E-IT-603 and Z-IT-603 (IT-603). IT-603 is a c-Rel inhibitor with an IC50 of 3 μM. IT-603 h

This product is for research use only, not for human use. We do not sell to patients.

Bioactivity

(E/Z)-IT-603 is a mixture of E-IT-603 and Z-IT-603 (IT-603). IT-603 is a c-Rel inhibitor with an IC50 of 3 μM. IT-603 has anti-tumor activity. (E/Z)-IT-603 is a promising modulator of T-cell responses in the context of graft-versus-host disease (GVHD) and malignant diseases[1].

Name

(E/Z)-IT-603

CAS

292168-90-2

Formula

C11H9BrN2O3S

Molar Mass

329.17

Appearance

Solid

Transport

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Reference

[1]. Yusuke Shono, et al. A small molecule c-Rel inhibitor reduces alloactivation of T-cells without compromising anti-tumor activity. Cancer Discov. 2014 May; 4(5): 578-591.

PeptideDB

(E/Z)-IT-603

CAS: 292168-90-2 F: C11H9BrN2O3S W: 329.17