| Bioactivity | (E/Z)-CCR-11 (Comp 12) is a selective CD38 inhibitor, with an IC50 of 20.8 μM against CD38 cyclase. (E/Z)-CCR-11 promotes increases in cellular NAD+ levels and interferon γ[1]. | ||||||||||||
| Name | (E/Z)-CCR-11 | ||||||||||||
| CAS | 301687-87-6 | ||||||||||||
| Formula | C15H8F3NO2S2 | ||||||||||||
| Molar Mass | 355.35 | ||||||||||||
| Appearance | 固体 | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
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| Reference | [1]. Thomas Z Benton, et al. Selective targeting of CD38 hydrolase and cyclase activity as an approach to immunostimulation. RSC Adv. 2021 Oct 11;11(53):33260-33270. |
(E/Z)-CCR-11
CAS: 301687-87-6 F: C15H8F3NO2S2 W: 355.35
(E/Z)-CCR-11 (Comp 12) is a selective CD38 inhibitor, with an IC50 of 20.8 μM against CD38 cyclase. (E/Z)-CCR-11promote
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