| Bioactivity | (E)-PHCCC is a positive allosteric modulator (PAM) for mGluR4, that enhances the activity of the receptor's endogenous ligand (glutamate), and exhibits activity in the calcium mobilization assay in CHO cells with an EC50 of 3.2 μM[1]. |
| CAS | 177610-87-6 |
| Formula | C17H14N2O3 |
| Molar Mass | 294.30 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Williams R, et al., Re-exploration of the PHCCC Scaffold: Discovery of Improved Positive Allosteric Modulators of mGluR4. ACS Chem Neurosci. 2010 Jun 16;1(6):411-419. |
(E)-PHCCC
CAS: 177610-87-6 F: C17H14N2O3 W: 294.30
(E)-PHCCC is a positive allosteric modulator (PAM) for mGluR4, that enhances the activity of the receptor's endogenous l
Sales Email：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.