| Bioactivity | (D-Phe12,Nle21,38,α-Me-Leu37)-CRF (12-41) (human, rat) is a CRF antagonist. (D-Phe12,Nle21,38,α-Me-Leu37)-CRF (12-41) (human, rat) prevents the IL-1a induced Luteinizing hormone (LH) inhibition[1]. |
| Name | (D-Phe12,Nle21,38,α-Me-Leu37)-CRF (12-41) (human, rat) |
| CAS | 150646-45-0 |
| Sequence | {d-Phe}-His-Leu-Leu-Arg-Glu-Val-Leu-Glu-{Nle}-Ala-Arg-Ala-Glu-Gln-Leu-Ala-Gln-Gln-Ala-His-Ser-Asn-Arg-Lys-{Leu(α-Me)}-{Nle}-Glu-Ile-Ile-NH2 |
| Shortening | {d-Phe}-HLLREVLE-{Nle}-ARAEQLAQQAHSNRK-{Leu(α-Me)}-{Nle}-EII-NH2 |
| Formula | C159H267N49O43 |
| Molar Mass | 3553.12 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Feng YJ, et al. An inhibitory effects of interleukin-1a on basal gonadotropin release in the ovariectomized rhesus monkey: reversal by a corticotropin-releasing factor antagonist. Endocrinology. 1991 Apr;128(4):2077-82. |
(D-Phe12,Nle21,38,α-Me-Leu37)-CRF (12-41) (human, rat)
CAS: 150646-45-0 F: C159H267N49O43 W: 3553.12
(D-Phe12,Nle21,38,α-Me-Leu37)-CRF (12-41) (human, rat) is a CRF antagonist. (D-Phe12,Nle21,38,α-Me-Leu37)-CRF (12-41)
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