Bioactivity | (9R)-RO7185876 (Compound example 16) is a γ-secretase inhibitor. (9R)-RO7185876 inhibits Αβ42 secretion. (9R)-RO7185876 can be used for the researches of Alzheimer's disease, cerebral amyloid angiopathy, hereditary cerebral hemorrhage with amyloidosis, multi-infarct dementia, dementia pugilistica or Down syndrome[1]. |
CAS | 2226077-86-5 |
Formula | C25H28F3N7 |
Molar Mass | 483.53 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Bjoern Bartels, et al. Bicyclic heteroaryl derivatives. WO2018083050. WIPO. 2018-05-11. |