Bioactivity | (2S,4R)-DS89002333 is the enantiomer of DS89002333 (HY-150072). DS89002333 is an orally active and potent PRKACA inhibitor, with an IC50 of 0.3 nM[1]. |
Name | (2S,4R)-DS89002333 |
Formula | C22H20ClF2N3O3 |
Molar Mass | 447.86 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Toyota A, et al. ovel protein kinase cAMP-Activated Catalytic Subunit Alpha (PRKACA) inhibitor shows anti-tumor activity in a fibrolamellar hepatocellular carcinoma model. Biochem Biophys Res Commun. 2022 Sep 17;621:157-161. |