| Bioactivity | (2R,4R)-APDC hydrate ((2R,4R)-4-Aminopyrrolidine-2,4-dicarboxylic acid hydrate) is a group II metabotropic glutamate receptor (mGluR) agonist. (2R,4R)-APDC hydrate affects cell proliferation by inhibiting glutamate release, enhancing motor responses produced by D1 receptor activation, or reducing brain-derived neurotrophic factor (BDNF) levels. (2R,4R)-APDC hydrate can be used in the study of epilepsy and other neurological diseases[1]. |
| Formula | C6H12N2O5 |
| Molar Mass | 192.17 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Feng Y B, et al. Effects of the group II mGlu receptor agonist 2R, 4R-APDC on dentate gyrus cell proliferation in the adult rat brain after diffuse brain injury[J]. Neurological research, 2011, 33(4): 381-388. |