(24S)-24,25-Dihydroxyvitamin D3

CAS: 55700-58-8 F: C27H44O3 W: 416.64

(24S)-24,25-Dihydroxyvitamin D3 ((24S)-24,25-Dihydroxycholecalciferol) is an inactive form of vitamin D3 which undergoes

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Bioactivity	(24S)-24,25-Dihydroxyvitamin D3 ((24S)-24,25-Dihydroxycholecalciferol) is an inactive form of vitamin D3 which undergoes various levels of hydroxylation to form active vitamin D3 analogs.
Invitro	(24S)-24,25-Dihydroxyvitamin D3 ((24S)-24,25-Dihydroxycholecalciferol) is a isomer of 24,25-dihydroxyvitamin D3. Vitamin D is metabolized in the liver to 25-hydroxyvitamin D3, and in the kidney to 1,25-dihydroxyvitamin D3 and 24,25-dihydroxyvitamin D3[5].
Name	(24S)-24,25-Dihydroxyvitamin D3
CAS	55700-58-8
Formula	C27H44O3
Molar Mass	416.64
Appearance	Solid
Transport	Room temperature in continental US; may vary elsewhere.
Storage	-20°C, protect from light, stored under nitrogen *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Reference	[1]. Yamada S, Ino E, Takayama H et al. Differences in the side-chain metabolism of vitamin D3 between chickens and rats. Proc Natl Acad Sci U S A. 1985 Nov;82(22):7485-9. [2]. Kobayashi N, Higashi T, Saito K et al. Specificity of polyclonal antibodies raised against a novel 24,25-dihydroxyvitamin D3-bovine serum albumin conjugant linked through the C-11alpha or C-3 position. J Steroid Biochem Mol Biol. 1997 May;62(1):79-87. [3]. Larsson D, Nemere I, Sundell K. Putative basal lateral membrane receptors for 24,25-dihydroxyvitamin D(3) in carp and Atlantic cod enterocytes: characterization of binding and effects on intracellular calcium regulation. J Cell Biochem. 2001 Aug 1-9;83(2) [4]. Nemere I, Yazzie-Atkinson D, Johns DO, Larsson D. Biochemical characterization and purification of a binding protein for 24,25-dihydroxyvitamin D3 from chick intestine. J Endocrinol. 2002 Jan;172(1):211-9.