| Bioactivity | (1R,3S)-RSL3 is the less active (1R,3S)-enantiomer of RSL3 ((1S,3R)-RSL3). (1R,3S)-RSL3 and RSL3 induce cell death in HT22 wild-type cells with EC50 values of 5.2 µM and 0.004 µM, rspectively[1]. |
| Invitro | (1R,3S)-RSL3（0.1 nM-100 µM；16 小时）诱导 HT22 野生型 (WT) 和 HT22 Bid CRISPR KO 细胞死亡，EC50 值分别为 5.2 µM 和 28.8 µM[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> (1R,3S)-RSL3 相关抗体: Cell Viability Assay[1] Cell Line: |
| CAS | 1219810-13-5 |
| Formula | C23H21ClN2O5 |
| Molar Mass | 440.88 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Shin D, et al. Nrf2 inhibition reverses resistance to GPX4 inhibitor-induced ferroptosis in head and neck cancer. Free Radic Biol Med. 2018 Dec;129:454-462. |
(1R,3S)-RSL3
CAS: 1219810-13-5 F: C23H21ClN2O5 W: 440.88
(1R,3S)-RSL3 is the less active (1R,3S)-enantiomer of RSL3 ((1S,3R)-RSL3). (1R,3S)-RSL3 and RSL3 induce cell death in HT
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