(-)-Carvone_product_DataBase

Bioactivity

(-)-Carvone is an insect neurotoxin and a irreversible acetylcholinesterase (AChE) inhibitor. (-)-Carvone can be used as a bird repellent, inhibits larval growth, decreases pupatation rate, and increases mortality of larvae[1][2].

Invitro

(-)-Carvone (3.04 mM; 30 min) inactivates eel AChE with Ki value of 2.19 mM[1].

In Vivo

(-)-Carvone (5% in absolute ethanol v/v, 20 μL; application to the thoraces ventral surfaces) inhibits AChE such as horse serum cholinesterase, house fly head cholinesterases, and head and thorax cholinesterases from the Madagascar roach in vitro[1].(-)-Carvone (0.05%-0.1% w/v; p.o.; 7 d) inhibits E. insulana larvae growth, decreases weight of larvae[2]. Animal Model:

Name

(-)-Carvone

CAS

6485-40-1

Formula

C10H14O

Molar Mass

150.22

Appearance

Liquid

Transport

Room temperature in continental US; may vary elsewhere.

Storage

Pure form	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Reference

[1]. Grundy D L, et al. Inhibition of acetylcholinesterases by pulegone-1, 2-epoxide[J]. Pesticide biochemistry and physiology, 1985, 23(3): 383-388. [2]. Meisner J, et al. The response of Earias insulana Boisd. larvae to phagodeterrent (–)‐carvone incorporated in an artificial diet 1[J]. Zeitschrift für Angewandte Entomologie, 1980, 90(1‐5): 80-82.

PeptideDB

(-)-Carvone

CAS: 6485-40-1 F: C10H14O W: 150.22