(-)-(S)-B-973B_product_DataBase

CAS: 2244989-34-0 F: C24H26F2N6O W: 452.50

(-)-(S)-B-973B is a potent allosteric agonist and positive allosteric modulator of α7 nAChR, with antinociceptive activ

This product is for research use only, not for human use. We do not sell to patients.

Bioactivity

(-)-(S)-B-973B is a potent allosteric agonist and positive allosteric modulator of α7 nAChR, with antinociceptive activity[1].

Target

α7 nAChR

Name

(-)-(S)-B-973B

CAS

2244989-34-0

Formula

C24H26F2N6O

Molar Mass

452.50

Appearance

Solid

Transport

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Reference

[1]. Garai S, et al. B-973, a Novel α7 nAChR Ago-PAM: Racemic and Asymmetric Synthesis, Electrophysiological Studies, and in Vivo Evaluation. ACS Med Chem Lett. 2018 Oct 11;9(11):1144-1148.

PeptideDB

(-)-(S)-B-973B

CAS: 2244989-34-0 F: C24H26F2N6O W: 452.50