| Bioactivity | (+)-U-50488 (hydrochloride) (+)-Trans-(1R,2R)-U-50488 hydrochloride) is a less active κ opioid receptor (KOR) agonist than the enantiomer of (-)-Trans-(1S,2S)-U-50488 (HY-15997)[1]. |
| Target | IC50: κ opioid receptor (KOR) |
| Invitro | (+)-U-50488 (hydrochloride) (+)-Trans-(1R,2R)-U-50488 hydrochloride) is a enantiomer of (-)-Trans-(1S,2S)-U-50488[1]. |
| Name | (+)-U-50488 hydrochloride |
| CAS | 114528-81-3 |
| Formula | C19H27Cl3N2O |
| Molar Mass | 405.79 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. DeCosta B, et al. Synthesis and absolute configuration of optically pure enantiomers of a kappa-opioid receptor selective agonist. FEBS Lett. 1987;223(2):335-339. |