Bioactivity | β-D-glucuronide-pNP-carbonate is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. |
Invitro | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1]. |
Name | β-D-glucuronide-pNP-carbonate |
CAS | 894095-98-8 |
Formula | C45H43N3O18 |
Molar Mass | 913.83 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337. |