| CAS | 181139-85-5 |
| Sequence | Z-Leu-Leu-4,5-dehydro-Leu-aldehyde |
| Sequence Single | Z-LL-4,5-dehydro-L-aldehyde |
| Molecular Formula | C26H39N3O5 |
| Molecular Weight | 473.61 |
| Synonyms | SIB 1281, Z-Leu-Leu-4,5-dehydro-Leu-CHO |
| Technology | Synthetic |
| Storage | -20°C, avoid light, cool and dry place |
| Application | Alzheimer’s Disease |
| Description | Z-Leu-Leu-4,5-dehydro-Leu-aldehyde also called SIB 1281, Z-Leu-Leu-4,5-dehydro-Leu-CHO, inhibited the formation of β- and γ-secretase derived amyloid β-protein (Aβ) with IC50 = 1.8 µM and stimulated the formation of α-secretase derived soluble amyloid precursor protein (sα) with an EC50 of 250 nM. |
Z-Leu-Leu-4,5-dehydro-Leu-aldehyde
CAS No.: 181139-85-5
Z-Leu-Leu-4,5-dehydro-Leu-aldehyde also called SIB 1281, Z-Leu-Leu-4,5-dehydro-Leu-CHO, inhibited the formation of β- a
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