| CAS | 210344-95-9 |
| Sequence | Z-Asp(OMe)-Glu(OMe)-Val-Asp(OMe)-FMK |
| Sequence Single | Z-D(OMe)E(OMe)VD(OMe)-FMK |
| Molecular Formula | C30H41FN4O12 |
| Molecular Weight | 668.67 |
| Technology | Synthetic |
| Storage | -20°C, avoid light, cool and dry place |
| Description | Z-DEVD-FMK is a specific and irreversible caspase-3 inhibitor with an IC50 of 18 μM. |
| References | 1. Identification of apoptosis-associated proteins in a human Burkitt lymphoma cell line. Brocksted et al (1998). J.Biol.Chem. 273 28057 PMID: 9774422 2. Involvement of caspase-3-like protease in the mechanism of cell death following focally evoked limbic seizures. Henshall et al (2000). J.Neurochem. 74 1215 PMID: 10693954 3. Apoptosis of NG108-15 cells induced by Bupren. hydrochloride occurs via the caspase-3 pathway. Kugawa et al (2000). Biol.Pharm.Bull. 23 930 PMID: 10963298 |