| CAS | 108334-68-5 |
| Sequence | H-Pro-Leu-Ala-Arg-Thr-Leu-Ser-Val-Ala-Gly-Leu-Pro-Gly-Lys-Lys-OH |
| Sequence Single | PLARTLSVAGLPGKK |
| Molecular Formula | C68H122N20O18 |
| Molecular Weight | 1507.84 |
| Synonyms | Calmodulin-Dependent Protein Kinase Substrate |
| Technology | Synthetic |
| Storage | -20°C, avoid light, cool and dry place |
| Description | Syntide 2 also called Calmodulin-Dependent Protein Kinase Substrate, a Ca2+- and calmodulin (CaM)-dependent protein kinase II (CaMKII) substrate peptide, selectively inhibits the gibberellin (GA) response, leaving constitutive and abscisic acid-regulated events unaffected. The sequence of syntide 2 is homologous to phosphorylation site 2 in glycogen synthase. |
| References | 1. Use of fragments of hirudin to investigate thrombin-hirudin interaction. S.Dennis et al., Eur. J. Biochem., 188, 61 (1990) 2. A novel highly specific and potent inhibitor of calmodulin-dependent protein kinase II. A.Ishida et al., Biochem. Biophys. Res. Commun., 212, 806 (1995) 3. Calcium-Dependent Protein Phosphorylation May Mediate the Gibberellic Acid Response in Barley Aleurone. Ritchie S, et al. Plant Physiol. 1998 Feb 1;116(2):765-76. |