| CAS | 51165-07-2 |
| Sequence | H-Gln-Phe-Phe-Gly-Leu-Met-NH2 |
| Sequence Single | QFFGLM-NH2 |
| Molecular Formula | C36H52N8O7S |
| Molecular Weight | 740.93 |
| Synonyms | Hexa-Substance P |
| Technology | Synthetic |
| Storage | -20°C, avoid light, cool and dry place |
| Description | Substance P (6-11) also called Hexa-Substance P, is the C-terminal hexapeptideamide of Substance P. Substance P (6-11) binds to NK-1 tachykinin receptor. Substance P (6-11) shows depolarization of motoneurons and a hypotensive effect. |
| References | 1. Substance P(6-11) and natural tachykinins interact with septide-sensitive tachykinin receptors coupled to a phospholipase C in the rat urinary bladder. Y Torrens, et al. Neuropeptides. 1997 Jun;31(3):243-51. 2. Effects of substance P and substance P-(6-11) on hormone release from isolated perfused pancreas: their opposite actions on rat and canine islets. Y Chiba, et al. Endocrinology. 1985 Nov;117(5):1996-2000. |