Stresscopin-Related Peptide (human) Stresscopin and Urocortin Catalog

CAS	348626-74-4
Sequence	H-His-Pro-Gly-Ser-Arg-Ile-Val-Leu-Ser-Leu-Asp-Val-Pro-Ile-Gly-Leu-Leu-Gln-Ile-Leu-Leu-Glu-Gln-Ala-Arg-Ala-Arg-Ala-Ala-Arg-Glu-Gln-Ala-Thr-Thr-Asn-Ala-Arg-Ile-Leu-Ala-Arg-Val-NH2
Sequence Single	HPGSRIVLSLDVPIGLLQILLEQARARAAREQATTNARILARV-NH2
Molecular Formula	C205H358N68O57
Molecular Weight	4687.52
Synonyms	SRP (human)
Technology	Synthetic
Storage	-20°C, avoid light, cool and dry place
Description	Stresscopin-Related Peptide (human) also called SRP (human), is a specific ligand for the corticotropin-releasing hormone receptor type 2 (CRHR2). Transcripts are expressed in brain and multiple peripheral tissues. Intraperitoneal injections of stresscopin-related peptide (human) suppresses heat-induced edema formation in anesthetized rats. It also decreases food intake and exhibits an inhibitory effect on gastric emptying activity. This CRHR2 agonist might represent an endogenous ligand for maintaining homeostasis after stress.
References	1. Human stresscopin and stresscopin-related peptide are selective ligands for the type 2 corticotropin-releasing hormone receptor. Hsu SY, et al. Nat Med. 2001 May;7(5):605-11.

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