CAS | 209006-05-3 |
Sequence | H-p-Chloro-Phe-D-Cys-β-(3-pyridyl)-Ala-D-Trp-Lys-Val-Cys-p-chloro-Phe-NH2 (Disulfide bond) |
Sequence Single | H-p-Chloro-Fc-β-(3-pyridyl)-AwKVC-p-chloro-F-NH2 |
Molecular Formula | C54H66Cl2N12O8S2 |
Molecular Weight | 1146.23 |
Technology | Synthetic |
Storage | -20°C, avoid light, cool and dry place |
Application | Cardiovascular System & Diseases |
Description | SB-710411 (Cpa-D-Cys-Pal-D-Trp-Lys-Val-Cys-Cpa-amide) is a urotensin ll receptor antagonist. It showed inhibition of the urotensin receptor binding / function and also potentiated endothelin-1 induced contraction in the rat isolated aorta. Liu et al. observed that SB-710411 arrests fibrosis in CCL4 cirrhotic rats. |