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SB-710411

CAS No.: 209006-05-3

SB-710411 (Cpa-D-Cys-Pal-D-Trp-Lys-Val-Cys-Cpa-amide) is a urotensin ll receptor antagonist. It showed inhibition of the
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CAS 209006-05-3
Sequence H-p-Chloro-Phe-D-Cys-β-(3-pyridyl)-Ala-D-Trp-Lys-Val-Cys-p-chloro-Phe-NH2 (Disulfide bond)
Sequence Single H-p-Chloro-Fc-β-(3-pyridyl)-AwKVC-p-chloro-F-NH2
Molecular Formula C54H66Cl2N12O8S2
Molecular Weight 1146.23
Technology Synthetic
Storage -20°C, avoid light, cool and dry place
Application Cardiovascular System & Diseases
Description SB-710411 (Cpa-D-Cys-Pal-D-Trp-Lys-Val-Cys-Cpa-amide) is a urotensin ll receptor antagonist. It showed inhibition of the urotensin receptor binding / function and also potentiated endothelin-1 induced contraction in the rat isolated aorta. Liu et al. observed that SB-710411 arrests fibrosis in CCL4 cirrhotic rats.