| CAS | 120972-53-4 |
| Sequence | H-Cys-Ser-Cys-Lys-Asp-Met-Thr-Asp-Lys-Glu-Cys-Leu-Tyr-Phe-Cys-His-Gln-Asp-Val-Ile-Trp-OH (Disulfide bonds between Cys1 and Cys15/Cys3 and Cys11) |
| Sequence Single | CSCKDMTDKECLYFCHQDVIW |
| Molecular Formula | C110H159N27O34S5 |
| Molecular Weight | 2563.96 |
| Synonyms | SRTX-B, Sarafotoxin S6b |
| Technology | Synthetic |
| Storage | -20°C, avoid light, cool and dry place |
| Description | Sarafotoxin B also called SRTX-B, Sarafotoxin S6b, is a vasoconstrictor peptide, and a non-selective endothelin receptor agonist. Sarafotoxin B can induce contraction in isolated human coronary arteries , the Ki values of Coronary artery, Saphenous vein and Coronary artery are 0.27, 0.55 and 19.5 nM, respectively. |
| References | 1. Comparison of the contractile effects and binding kinetics of endothelin-1 and sarafotoxin S6b in rat isolated renal artery. P S Devadason et al. Br J Pharmacol. 1997 May;121(2):253-63. |