PeptideDB

Sarafotoxin A

CAS No.: 126738-34-9

Sarafotoxin A also called SRTX-A, S6A, Sarafotoxin S6a, a sarafotoxin analogue, is a endothelin receptor agonist and has
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CAS 126738-34-9
Sequence H-Cys-Ser-Cys-Lys-Asp-Met-Thr-Asp-Lys-Glu-Cys-Leu-Asn-Phe-Cys-His-Gln-Asp-Val-Ile-Trp-OH (Disulfide bonds between Cys1 and Cys15/Cys3 and Cys11)
Sequence Single CSCKDMTDKECLNFCHQDVIW
Molecular Formula C105H156N28O34S5
Molecular Weight 2514.89
Synonyms SRTX-A, S6A, Sarafotoxin S6a
Technology Synthetic
Storage -20°C, avoid light, cool and dry place
Description Sarafotoxin A also called SRTX-A, S6A, Sarafotoxin S6a, a sarafotoxin analogue, is a endothelin receptor agonist and has an ETA/ETB selectivity profile similar to that of Endothelin-3. Sarafotoxin A elicits the pig coronary artery with an EC50 value of 7.5 nM.
References 1.  Differences between endothelin receptors mediating contraction of guinea-pig aorta and pig coronary artery. P Schoeffter, et al. Eur J Pharmacol.