CAS | 126738-34-9 |
Sequence | H-Cys-Ser-Cys-Lys-Asp-Met-Thr-Asp-Lys-Glu-Cys-Leu-Asn-Phe-Cys-His-Gln-Asp-Val-Ile-Trp-OH (Disulfide bonds between Cys1 and Cys15/Cys3 and Cys11) |
Sequence Single | CSCKDMTDKECLNFCHQDVIW |
Molecular Formula | C105H156N28O34S5 |
Molecular Weight | 2514.89 |
Synonyms | SRTX-A, S6A, Sarafotoxin S6a |
Technology | Synthetic |
Storage | -20°C, avoid light, cool and dry place |
Description | Sarafotoxin A also called SRTX-A, S6A, Sarafotoxin S6a, a sarafotoxin analogue, is a endothelin receptor agonist and has an ETA/ETB selectivity profile similar to that of Endothelin-3. Sarafotoxin A elicits the pig coronary artery with an EC50 value of 7.5 nM. |
References | 1. Differences between endothelin receptors mediating contraction of guinea-pig aorta and pig coronary artery. P Schoeffter, et al. Eur J Pharmacol. |