| CAS | 112540-82-6 |
| Sequence | H-Ala-Val-Ser-Glu-His-Gln-Leu-Leu-His-Asp-Lys-Gly-Lys-Ser-Ile-Gln-Asp-Leu-Arg-Arg-Arg-Phe-Phe-Leu-His-His-Leu-Ile-Ala-Glu-Ile-His-Thr-Ala-OH |
| Sequence Single | AVSEHQLLHDKGKSIQDLRRRFFLHHLIAEIHTA |
| Molecular Formula | C180H287N57O48 |
| Molecular Weight | 4017.61 |
| Synonyms | pTHrP (1-34) (human, mouse, rat), Hypercalcemia of Malignancy Factor (1-34) (human, mouse, rat) |
| Technology | Synthetic |
| Storage | -20°C, avoid light, cool and dry place |
| Application | Osteoporosis Research |
| Description | pTH-Related Protein (1-34) (human, mouse, rat) also called pTHrP (1-34) (human, mouse, rat), Hypercalcemia of Malignancy Factor (1-34) (human, mouse, rat). V.Paspaliaris et al. showed that daily administration of pTHrP (1-34) to rats was anabolic on bone by increasing bone formation. This treatment could inhibit the rapid decline in bone formation due to denervation. |
| References | 1. How an enzyme tames reactive intermediates: positioning of the active-site components of lysine 2,3-aminomutase during enzymatic turnover as determined by ENDOR spectroscopy. N.S.Lees et al., J. Am. Chem. Soc., 128, 10145 (2006) 2. Parathyroid hormone-related protein purified from a human lung cancer cell line. V.Paspaliaris et al., Bone, 16, 141S, abstract (1995) 3. Parathyroid hormone-related protein of malignancy: active synthetic fragments. J.M.Moseley et al., Proc. Natl. Acad. Sci. USA, 84, 5048 (1987) 4. Parathyroid hormone-related protein purified from a human lung cancer cell line. B.E.Kemp et al., Science, 238, 1568 (1987) |
pTH-Related Protein (1-34) (human, mouse, rat)
CAS No.: 112540-82-6
pTH-Related Protein (1-34) (human, mouse, rat) also called pTHrP (1-34) (human, mouse, rat), Hypercalcemia of Malignancy
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