CAS | 126391-27-3 |
Sequence | H-Ala-Val-Ser-Glu-His-Gln-Leu-Leu-His-Asp-Lys-Gly-Lys-Ser-Ile-Gln-OH |
Sequence Single | AVSEHQLLHDKGKSIQ |
Molecular Formula | C77H128N24O25 |
Molecular Weight | 1790.01 |
Synonyms | Hypercalcemia of Malignancy Factor (1-16) (human, mouse, rat), pTHrP (1-16) |
Technology | Synthetic |
Storage | -20°C, avoid light, cool and dry place |
Description | pTH-Related Protein (1-16) (human, mouse, rat) also called Hypercalcemia of Malignancy Factor (1-16) (human, mouse, rat), pTHrP (1-16), is an N-terminal fragment of pTH-related protein lacking a pTH/pTHrP-receptor binding domain. Schlüter et al. observed that pTH-Related Protein (1-16) could activate the cardiac ET-A receptor. On the other hand, Langlois et al. could not detect binding of pTH-Related Protein (1-16) to ET-A nor to the ET-B receptor. |