CAS | 235433-36-0 |
Sequence | H-Thr-Pro-Asp-Ile-Asn-Pro-Ala-Trp-Tyr-Ala-Ser-Arg-Gly-Ile-Arg-Pro-Val-Gly-Arg-Phe-NH2 |
Sequence Single | TPDINPAWYASRGIRPVGRF-NH2 |
Molecular Formula | C104H158N32O26 |
Molecular Weight | 2272.6 |
Synonyms | PrRP20 (human), Preprolactin (34-53) (human) |
Technology | Synthetic |
Storage | -20°C, avoid light, cool and dry place |
Description | Prolactin-Releasing Peptide (12-31) (human) also called PrRP20 (human), Preprolactin (34-53) (human), is a fragment of the prolactin releasing peptide (PrRP). Prolactin-Releasing Peptide (12-31) (human) is a high affinity GPR10 ligand that cause the release of the prolactin. |
References | 1. Anatomical distribution of prolactin-releasing peptide and its receptor suggests additional functions in the central nervous system and periphery. Roland BL, et al. Endocrinology. 1999 Dec;140(12):5736-45. 2. Characterization of the binding of [(125)I]-human prolactin releasing peptide (PrRP) to GPR10, a novel G protein coupled receptor. Langmead CJ, et al. Br J Pharmacol. 2000 Oct;131(4):683-8. 3. Prolactin releasing peptide (PrRP) stimulates luteinizing hormone (LH) and follicle stimulating hormone (FSH) via a hypothalamic mechanism in male rats. Seal LJ, et al. Endocrinology. 2000 May;141(5):1909-12. |