| CAS | 157382-69-9 |
| Sequence | Ac-Asp-Tyr(PO3H2)-Val-Pro-Met-Leu-NH2 |
| Sequence Single | Ac-D(p)YVPML-NH2 |
| Molecular Formula | C36H56N7O13PS |
| Molecular Weight | 857.92 |
| Technology | Synthetic |
| Storage | -20°C, avoid light, cool and dry place |
| Description | Ac-Asp-Tyr(PO3H2)-Val-Pro-Met-Leu-NH2 is a short phosphotyrosine-containing peptide, it was able to compete with protein ligands for binding to SH2 domains (IC50 = 0.15 µM) and to afford starting points for SH2 domain inhibitor design. SH2 domains participate in protein tyrosine kinase (PTK)-mediated cellular signal. |
| References | 1. Nonhydrolyzable phosphotyrosyl mimetics for the preparation of phosphatase-resistant SH2 domain inhibitors. Burke TR Jr, et al. Biochemistry. 1994 May 31;33(21):6490-4. |
Ac-Asp-Tyr(PO3H2)-Val-Pro-Met-Leu-NH2
CAS No.: 157382-69-9
Ac-Asp-Tyr(PO3H2)-Val-Pro-Met-Leu-NH2 is a short phosphotyrosine-containing peptide, it was able to compete with protein
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