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Prolactin-Releasing Peptide (1-31) (human)

CAS No.: 215510-22-8

Prolactin-Releasing Peptide (1-31) (human) also called PrRP31 (human), Preprolactin (23-53) (human), is a high affinity
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CAS 215510-22-8
Sequence H-Ser-Arg-Thr-His-Arg-His-Ser-Met-Glu-Ile-Arg-Thr-Pro-Asp-Ile-Asn-Pro-Ala-Trp-Tyr-Ala-Ser-Arg-Gly-Ile-Arg-Pro-Val-Gly-Arg-Phe-NH2
Sequence Single SRTHRHSMEIRTPDINPAWYASRGIRPVGRF-NH2
Molecular Formula C160H252N56O42S
Molecular Weight 3664.18
Synonyms PrRP31 (human), Preprolactin (23-53) (human)
Technology Synthetic
Storage -20°C, avoid light, cool and dry place
Description Prolactin-Releasing Peptide (1-31) (human) also called PrRP31 (human), Preprolactin (23-53) (human), is a high affinity GPR10 ligand that cause the release of the prolactin. Prolactin-Releasing Peptide (1-31) (human) binds to GPR10 for human and rats with Ki values of 1.03 nM and 0.33 nM, respectively. Prolactin-Releasing Peptide (1-31) (human) can be used for the research of the hypothalamo-pituitary axis.
References 1.  Characterization of the binding of [(125)I]-human prolactin releasing peptide (PrRP) to GPR10, a novel G protein coupled receptor. Langmead CJ, et al. Br J Pharmacol. 2000 Oct;131(4):683-8. 2.  Prolactin releasing peptide (PrRP) stimulates luteinizing hormone (LH) and follicle stimulating hormone (FSH) via a hypothalamic mechanism in male rats. L J Seal, et al. Endocrinology. 2000 May;141(5):1909-12.