[Phe8Ψ(CH-NH)-Arg9]-Bradykinin Various Peptides Catalog

CAS	118122-39-7
Sequence	H-Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Ψ-(CH2-NH)-Arg-OH
Sequence Single	RPPGFSPF-Ψ-(CH2-NH)-R
Molecular Formula	C50H75N15O10
Molecular Weight	1046.23
Technology	Synthetic
Storage	-20°C, avoid light, cool and dry place
Description	[Phe8Ψ(CH-NH)-Arg9]-Bradykinin is a selective bradykinin B2 receptor agonist that is resistant to carboxypeptidase cleavage. 5-fold more potent and exhibits a more prolonged duration of action than bradykinin in vivo.
References	1. [Phe8Ψ(CH2-NH)Arg9]bradykinin, a B2 receptor selective agonist which is not broken down by either kininase I or kininase II. Drapeau et al (1988). Eur.J.Pharmacol. 155 193 PMID: 2907489 2. Kinin receptors: functional aspects. Marceau et al (2002). Int.Immunopharmacol. 2 1729 PMID: 12489786 3. International union of pharmacology. XLV. Classification of the kinin receptor family: from molecular mechanisms to pathophysiological consequences. Leeb-Lundberg et al (2005). Pharmacol.Rev. 57 27 PMID: 15734727

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