CAS | 202933-49-1 |
Sequence | H-Ser-Leu-Ile-Gly-Lys-Val-OH |
Sequence Single | SLIGKV |
Molecular Formula | C28H53N7O8 |
Molecular Weight | 615.77 |
Synonyms | SLIGKV, Proteinase Activated Receptor 2 (1-6) (human), Thrombin Receptor-Like 1 (1-6) (human), Coagulation Factor II Receptor-Like 1 (1-6) (human) |
Technology | Synthetic |
Storage | -20°C, avoid light, cool and dry place |
Application | Hematology |
Description | PAR-2 (1-6) (human) also called SLIGKV, Proteinase Activated Receptor 2 (1-6) (human), Thrombin Receptor-Like 1 (1-6) (human), Coagulation Factor II Receptor-Like 1 (1-6) (human), is a PAR-2 agonist, it can be used for the investigation of receptor functions. |
References | 1. Bacterial beta-peptidyl aminopeptidases with unique substrate specificities for beta-oligopeptides and mixed beta,alpha-oligopeptides. B.Geueke et al., FEBS J., 273, 5261 (2006) 2. Purification and characterization of a trypsin-like serine proteinase from rat brain slices that degrades laminin and type IV collagen and stimulates protease-activated receptor-2. K.Sawada et al., J. Neurochem., 74, 1731 (2000) 3. Potent and metabolically stable agonists for protease-activated receptor-2: evaluation of activity in multiple assay systems in vitro and in vivo. A.Kawabata et al., J. Pharmacol. Exp. Ther., 309, 1098 (2004) |