| CAS | 140436-67-5 |
| Sequence | H-Ser-Phe-Phe-Leu-Arg-Asn-OH |
| Sequence Single | SFFLRN |
| Molecular Formula | C37H54N10O9 |
| Molecular Weight | 782.9 |
| Synonyms | SFFLRN, Proteinase Activated Receptor 1 (1-6) (mouse, rat), Thrombin Receptor (1-6) (mouse, rat) |
| Technology | Synthetic |
| Storage | -20°C, avoid light, cool and dry place |
| Application | Cardiovascular System & Diseases|Hematology |
| Description | PAR-1 (1-6) (mouse, rat) also called SFFLRN, Proteinase Activated Receptor 1 (1-6) (mouse, rat), Thrombin Receptor (1-6) (mouse, rat), is a PAR-1 agonist. |
| References | 1. Receptor subtype-specific pronociceptive and analgesic actions of galanin in the spinal cord: selective actions via GalR1 and GalR2 receptors. H.-X.Liu et al., Proc. Natl. Acad. Sci. USA, 98, 9960 (2001) 2. Thrombin cleaves the high molecular weight forms of basic fibroblast growth factor (FGF-2): a novel mechanism for the control of FGF-2 and thrombin activity. P.J.Yu et al., Oncogene, 27, 2594 (2008) 3. Activated protein C ameliorates diabetic nephropathy by epigenetically inhibiting the redox enzyme p66Shc. F.Bock et al., Proc. Natl. Acad. Sci. USA, 110, 648 (2013) |