CAS | 179986-89-1 |
Sequence | H-Ala-Pro-Leu-Glu-Pro-Glu-Tyr-Pro-Gly-Asp-Asn-Ala-Thr-Pro-Glu-Gln-Met-Ala-Gln-Tyr-Ala-Ala-Glu-Leu-Arg-Arg-Tyr-Ile-Asn-Met-Leu-Thr-Arg-Pro-Arg-Tyr-NH2 |
Sequence Single | APLEPEYPGDNATPEQMAQYAAELRRYINMLTRPRY-NH2 |
Molecular Formula | C186H287N53O56S2 |
Molecular Weight | 4225.78 |
Technology | Synthetic |
Storage | -20°C, avoid light, cool and dry place |
Application | Gastrointestinal Research |
Description | Pancreatic Polypeptide (bovine), a 36-amino acid, straight chain polypeptide derived primarily from the pancreas, inhibits secretin- and cholecystokinin-stimulated pancreatic secretion; Pancreatic Polypeptide (bovine) acts as an agonist of NPY receptor, with high affinity at NPYR4. |
References | 1. A study on the release mechanism of vasopressin and oxytocin. H.Hashimoto et al., Neuropeptides, 12, 199 (1988) 2. Influence of neuropeptide Y and pancreatic polypeptide on islet function and beta-cell survival. Khan D, et al. Biochim Biophys Acta. 2017 Apr;1861(4):749-758. 3. Action of pancreatic polypeptide on rat pancreatic secretion: in vivo and in vitro. Louie DS, et al. Am J Physiol. 1985 Oct;249(4 Pt 1):G489-95. |