| CAS | 112208-00-1 |
| Sequence | Palmitoyl-Cys((RS)-2,3-di(palmitoyloxy)-propyl)-Ser-Lys-Lys-Lys-Lys-OH |
| Sequence Single | Pam3-CSKKKK |
| Molecular Formula | C81H156N10O13S |
| Molecular Weight | 1510.26 |
| Synonyms | Pam3Cys-Ser-Lys-Lys-Lys-Lys-OH, Pam3CSK4 |
| Technology | Synthetic |
| Storage | -20°C, avoid light, cool and dry place |
| Application | Immunomodulating Agents|Veterinary Medicine |
| Description | Palmitoyl-Cys((RS)-2,3-di(palmitoyloxy)-propyl)-Ser-Lys-Lys-Lys-Lys-OH also called Pam3Cys-Ser-Lys-Lys-Lys-Lys-OH, Pam3CSK4, is a non-toxic lipopeptide, it is a highly effective adjuvant for parenteral, oral and nasal immunizations. It readily dissolves in aqueous solvents and might also be applicable for DNA immunizations. |
| References | 1. Proteinase-activated receptor-2-activating peptides induce leukocyte rolling, adhesion, and extravasation in vivo. N.Vergnolle, J. Immunol., 163, 5064 (1999) 2. Synthesis of novel immunologically active tripalmitoyl-S-glycerylcysteinyl lipopeptides as useful intermediates for immunogen preparations. J.Metzger et al., Int. J. Pept. Protein Res., 37, 46 (1991) |