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Palmitoyl-Cys((RS)-2,3-di(palmitoyloxy)-propyl)-Ala-Gly-OH

CAS No.: 117858-54-5

Palmitoyl-Cys((RS)-2,3-di(palmitoyloxy)-propyl)-Ala-Gly-OH also called Pam3Cys-Ala-Gly-OH, Pam3CAG, is a synthetic lipop
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CAS 117858-54-5
Sequence Palmitoyl-Cys((RS)-2,3-di(palmitoyloxy)-propyl)-Ala-Gly-OH
Sequence Single Pam3-CAG
Molecular Formula C59H111N3O9S
Molecular Weight 1038.61
Synonyms Pam3Cys-Ala-Gly-OH, Pam3CAG
Technology Synthetic
Storage -20°C, avoid light, cool and dry place
Application Immunomodulating Agents
Description Palmitoyl-Cys((RS)-2,3-di(palmitoyloxy)-propyl)-Ala-Gly-OH also called Pam3Cys-Ala-Gly-OH, Pam3CAG, is a synthetic lipopeptide analog, it corresponds to the N-terminal region of a bacterial lipoprotein, it is a potent activator of macrophages. It is suggested that the uptake of Pam3CAG into macrophages involves the aggregation of membrane proteins.
References 1.  Sequential activation of ICE-like and CPP32-like proteases during Fas-mediated apoptosis. M.Enari et al., Nature, 380, 723 (1996)