PACAP-38 (31-38) (human, chicken, mouse, ovine, porcine, rat) PACAP and Fragments Catalog

CAS	138764-85-9
Sequence	H-Tyr-Lys-Gln-Arg-Val-Lys-Asn-Lys-NH2
Sequence Single	YKQRVKNK-NH2
Molecular Formula	C47H83N17O11
Molecular Weight	1062.28
Synonyms	Pituitary Adenylate Cyclase Activating Polypeptide-38 (31-38) (human, chicken, mouse, ovine, porcine, rat)
Technology	Synthetic
Storage	-20°C, avoid light, cool and dry place
Description	PACAP-38 (31-38) (human, chicken, mouse, ovine, porcine, rat) also called Pituitary Adenylate Cyclase Activating Polypeptide-38 (31-38) (human, chicken, mouse, ovine, porcine, rat), is a PAC1 receptor activator and increases the α-secretase activity. PACAP-38 (31-38) (human, chicken, mouse, ovine, porcine, rat) elevates cytosolic Ca2+, increases proliferation and increases phosphorylation of extracellular regulates kinase (ERK) and the epidermal growth factor receptor (EGFR). PACAP-38 (31-38) (human, chicken, mouse, ovine, porcine, rat) demonstrates potent, efficacious, and sustained stimulatory effects on sympathetic neuronal NPY and catecholamine production. PACAP-38 (31-38) (human, chicken, mouse, ovine, porcine, rat) can be used for neurotrophic and neuroprotective research.
References	1. PAC1 regulates receptor tyrosine kinase transactivation in a reactive oxygen species-dependent manner. Moody TW, et, al. Peptides. 2019 Oct;120:170017. 2. The neuropeptide PACAP promotes the alpha-secretase pathway for processing the Alzheimer amyloid precursor protein. Kojro E, et, al. FASEB J. 2006 Mar;20(3):512-4. 3. Pituitary adenylate cyclase-activating polypeptides, PACAP-38 and PACAP-27, regulation of sympathetic neuron catecholamine, and neuropeptide Y expression through activation of type I PACAP/VIP receptor isoforms. Braas KM, et, al. Ann N Y Acad Sci. 1996 De

PeptideDB

PACAP-38 (31-38) (human, chicken, mouse, ovine, porcine, rat)

CAS No.: 138764-85-9