| CAS | 144025-82-1 |
| Sequence | H-Gln-Met-Ala-Val-Lys-Lys-Tyr-Leu-Ala-Ala-Val-Leu-Gly-Lys-Arg-Tyr-Lys-Gln-Arg-Val-Lys-Asn-Lys-NH2 |
| Sequence Single | QMAVKKYLAAVLGKRYKQRVKNK-NH2 |
| Molecular Formula | C123H215N39O28S |
| Molecular Weight | 2720.37 |
| Synonyms | Pituitary Adenylate Cyclase Activating Polypeptide-38 (16-38) (human, chicken, mouse, ovine, porcine, rat) |
| Technology | Synthetic |
| Storage | -20°C, avoid light, cool and dry place |
| Description | PACAP-38 (16-38) (human, chicken, mouse, ovine, porcine, rat) also called Pituitary Adenylate Cyclase Activating Polypeptide-38 (16-38) (human, chicken, mouse, ovine, porcine, rat), is the C-terminal fragment of PACAP-38. It is very effective in inducing histamine release from rat peritoneal mast cells. It demonstrates potent, efficacious, and sustained stimulatory effects on sympathetic neuronal NPY and catecholamine production. PACAP is a potent activator of cAMP formation. |
| References | 1. Atrial natriuretic prohormone peptides 1-30, 31-67, and 79-98 vasodilate the aorta. D.L.Vesely et al., Biochem. Biophys. Res. Commun., 148, 1540 (1987) 2. Pituitary adenylate cyclase-activating polypeptides, PACAP-38 and PACAP-27, regulation of sympathetic neuron catecholamine, and neuropeptide Y expression through activation of type I PACAP/VIP receptor isoforms. Braas KM, et al. Ann N Y Acad Sci. 1996 Dec 3. Mechanism of action of pituitary adenylate cyclase-activating polypeptide (PACAP) in human nonfunctioning pituitary tumors. Lania A, et al. J Neuroendocrinol. 1995 Sep;7(9):695-702. |
PACAP-38 (16-38) (human, chicken, mouse, ovine, porcine, rat)
CAS No.: 144025-82-1
PACAP-38 (16-38) (human, chicken, mouse, ovine, porcine, rat) also called Pituitary Adenylate Cyclase Activating Polypep
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