| CAS | 202801-92-1 |
| Sequence | H-Arg-Pro-Gly-Pro-Pro-Gly-Leu-Gln-Gly-Arg-Leu-Gln-Arg-Leu-Leu-Gln-Ala-Asn-Gly-Asn-His-Ala-Ala-Gly-Ile-Leu-Thr-Met-NH2 |
| Sequence Single | RPGPPGLQGRLQRLLQANGNHAAGILTM-NH2 |
| Molecular Formula | C126H214N45O34S |
| Molecular Weight | 2936.44 |
| Synonyms | Hypocretin-2 (mouse, rat) |
| Technology | Synthetic |
| Storage | -20°C, avoid light, cool and dry place |
| Description | Orexin B (mouse, rat) also called Hypocretin-2 (mouse, rat), is an endogenous agonist at Orexin receptor with Kis of 420 and 36 nM for OX1 and OX2, respectively. |
| References | 1. Orexins: a new family of neuropeptides. Smart D, et al. Br J Anaesth. 1999 Nov;83(5):695-7. 2. Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior. Sakurai T, et al. Cell. 1998 Feb 20;92(4):573-85. 3. Orexin B inhibits proliferation and stimulates specialized function of cultured rat calvarial osteoblast-like cells. Ziolkowska A, et al. Int J Mol Med. 2008;22(6):749-755. 4. Orexin-B modulates synaptic transmission of rod bipolar cells in rat retina. Zhang G, et al. Neuropharmacology. 2018;133:38-50. |