| CAS | 532932-99-3 |
| Sequence | H-Arg-Ser-Gly-Pro-Pro-Gly-Leu-Gln-Gly-Arg-Ala-Gln-Arg-Leu-D-Leu-Gln-Ala-Ser-Gly-Asn-His-Ala-Ala-Gly-Ile-Leu-Thr-Met-NH2 |
| Sequence Single | RSGPPGLQGRAQRLlQASGNHAAGILTM-NH2 |
| Molecular Formula | C120H206N44O35S |
| Molecular Weight | 2857.3 |
| Technology | Synthetic |
| Storage | -20°C, avoid light, cool and dry place |
| Description | (Ala11,D-Leu15)-Orexin B (human) is a selective agonist of the orexin-2 receptor. This peptide showed a 400-fold selectivity for the orexin-2 receptor (EC50 = 0.13 nM) over the orexin-1 receptor (EC50 = 52 nM). |
| References | 1. Development of an orexin-2 receptor selective agonist, [Ala(11), D-Leu(15)]orexin-B. Asahi S, et al. Bioorg Med Chem Lett. 2003;13(1):111-113. |
(Ala11,D-Leu15)-Orexin B (human)
CAS No.: 532932-99-3
(Ala11,D-Leu15)-Orexin B (human) is a selective agonist of the orexin-2 receptor. This peptide showed a 400-fold selecti
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