PeptideDB

Myristoyl-Arg-Lys-Arg-Thr-Leu-Arg-Arg-Leu-OH

CAS No.: 152246-40-7

Myristoyl-Arg-Lys-Arg-Thr-Leu-Arg-Arg-Leu-OH also called N-m-RKRTLRRL, is a N-Myristylated peptide. N-Myristylation prov
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CAS 152246-40-7
Sequence Myristoyl-Arg-Lys-Arg-Thr-Leu-Arg-Arg-Leu-OH
Sequence Single Myr-RKRTLRRL
Molecular Formula C60H117N21O11
Molecular Weight 1308.72
Synonyms N-m-RKRTLRRL
Technology Synthetic
Storage -20°C, avoid light, cool and dry place
Description Myristoyl-Arg-Lys-Arg-Thr-Leu-Arg-Arg-Leu-OH also called N-m-RKRTLRRL, is a N-Myristylated peptide. N-Myristylation provided the octapeptide with an inhibitory activity against protein kinase C (PKC)-catalyzed Ca2+ and phosphatidylserine-dependent histone phosphorylation (IC50 = 5 µM). It has been shown that Myr-RKRTLRRL is the first synthetic PKC inhibitor with demonstrated pharmacological activity in intact cells.