PeptideDB

Myosin Light Chain Kinase (480-501)

CAS No.: 313642-00-1

Myosin Light Chain Kinase (480-501) inhibited calmodulin-dependent activation of the smooth muscle myosin light chain ki
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CAS 313642-00-1
Sequence H-Ala-Lys-Lys-Leu-Ser-Lys-Asp-Arg-Met-Lys-Lys-Tyr-Met-Ala-Arg-Arg-Lys-Trp-Gln-Lys-Thr-Gly-NH2
Sequence Single AKKLSKDRMKKYMARRKWQKTG-NH2
Molecular Formula C120H209N41O28S2
Molecular Weight 2738.37
Technology Synthetic
Storage -20°C, avoid light, cool and dry place
Description Myosin Light Chain Kinase (480-501) inhibited calmodulin-dependent activation of the smooth muscle myosin light chain kinase with an IC50 of 46 nM. At saturating concentrations of calmodulin, it inhibited myosin light chain and synthetic peptide substrate phosphorylation competitively with IC50 values of 2.7 and 0.9 µM, respectively.