CAS | 313642-00-1 |
Sequence | H-Ala-Lys-Lys-Leu-Ser-Lys-Asp-Arg-Met-Lys-Lys-Tyr-Met-Ala-Arg-Arg-Lys-Trp-Gln-Lys-Thr-Gly-NH2 |
Sequence Single | AKKLSKDRMKKYMARRKWQKTG-NH2 |
Molecular Formula | C120H209N41O28S2 |
Molecular Weight | 2738.37 |
Technology | Synthetic |
Storage | -20°C, avoid light, cool and dry place |
Description | Myosin Light Chain Kinase (480-501) inhibited calmodulin-dependent activation of the smooth muscle myosin light chain kinase with an IC50 of 46 nM. At saturating concentrations of calmodulin, it inhibited myosin light chain and synthetic peptide substrate phosphorylation competitively with IC50 values of 2.7 and 0.9 µM, respectively. |