| CAS | 163158-19-8 |
| Sequence | H-Met-Glu-Val-Gly-Trp-Tyr-Arg-Pro-Pro-Phe-Ser-Arg-Val-Val-His-Leu-Tyr-Arg-Asn-Gly-Lys-OH |
| Sequence Single | MEVGWYRPPFSRVVHLYRNGK |
| Molecular Formula | C120H179N35O28S |
| Molecular Weight | 2592.03 |
| Synonyms | MOG (35-55) (human) |
| Technology | Synthetic |
| Storage | -20°C, avoid light, cool and dry place |
| Application | Multiple Sclerosis |
| Description | Myelin Oligodendrocyte Glycoprotein (35-55) (human) also called MOG (35-55) (human). In contrast to the encephalitogenic rat homolog, myelin oligodendrocyte glycoprotein (35-55) (human) does not appear to be a major T-cell epitope in multiple sclerosis propably due to its lower amount of helical structure formed when dissolved in micellar sodium dodecyl sulfate, a membrane mimicking solvent. |
| References | 1. A role for neuropeptide W in the regulation of feeding behavior. M.S.Mondal et al., Endocrinology, 144, 4729 (2003) 2. Marmoset fine B cell and T cell epitope specificities mapped onto a homology model of the extracellular domain of human myelin oligodendrocyte glycoprotein. M.F.Mesleh et al., Neurobiol. Dis., 9, 160 (2002) 3. Predominance of the autoimmune response to myelin oligodendrocyte glycoprotein (MOG) in multiple sclerosis: reactivity to the extracellular domain of MOG is directed against three main regions. N.Kerlero de Rosbo et al., Eur. J. Immunol., 27, 3059 (1997) |
Myelin Oligodendrocyte Glycoprotein (35-55) (human)
CAS No.: 163158-19-8
Myelin Oligodendrocyte Glycoprotein (35-55) (human) also called MOG (35-55) (human). In contrast to the encephalitogenic
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