PeptideDB

M 1145

CAS No.: 1172089-00-7

M 1145 is a potent and selective galanin receptor 2 (GAL2) agonist (EC50 = 38 nM, Ki values are 6.55, 497 and 587 nM at
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CAS 1172089-00-7
Sequence H-Arg-Gly-Arg-Gly-Asn-Trp-Thr-Leu-Asn-Ser-Ala-Gly-Tyr-Leu-Leu-Gly-Pro-Val-Leu-Pro-Pro-Pro-Ala-Leu-Ala-Leu-Ala-NH2
Sequence Single RGRGNWTLNSAGYLLGPVLPPPALALA-NH2
Molecular Formula C128H205N37O32
Molecular Weight 2774.26
Technology Synthetic
Storage -20°C, avoid light, cool and dry place
Description M 1145 is a potent and selective galanin receptor 2 (GAL2) agonist (EC50 = 38 nM, Ki values are 6.55, 497 and 587 nM at GAL2, GAL3 and GAL1 respectively). M 1145 has an additive effect on the signal transduction of galanin.
References 1.  A novel GalR2-specific peptide agonist. Runesson et al (2009). Neuropeptides 43 187 PMID: 19467704