| CAS | 1219444-22-0 |
| Sequence | H-Cys-Thr-Cys-Lys-Asp-Met-Thr-Asp-Glu-Glu-Cys-Leu-Asn-Phe-Cys-His-Gln-Asp-Val-Ile-Trp-OH (Disulfide bonds between Cys1 and Cys15/Cys3 and Cys11) |
| Sequence Single | CTCKDMTDEECLNFCHQDVIW |
| Molecular Formula | C105H153N27O36S5 |
| Molecular Weight | 2529.83 |
| Synonyms | (Lys4)-SRTX-C, (Lys4)-S6C, [Lys4] Sarafotoxin S6c |
| Technology | Synthetic |
| Storage | -20°C, avoid light, cool and dry place |
| Application | Cardiovascular System & Diseases |
| Description | (Lys4)-Sarafotoxin C also called (Lys4)-SRTX-C, (Lys4)-S6C, [Lys4] Sarafotoxin S6c, a sarafotoxin analogue, is a potent and partial agonist of endothelin receptor. (Lys4)-Sarafotoxin C elicits contraction of pig coronary artery, with an EC50 of 1.5 nM. |
| References | 1. Differences between endothelin receptors mediating contraction of guinea-pig aorta and pig coronary artery. Schoeffter P, et al. Eur J Pharmacol. 1993 Nov 9;249(2):199-206. |