| CAS | 37553-80-3 |
| Sequence | H-Phe-Pro-Arg-OH |
| Sequence Single | FPR |
| Molecular Formula | C20H30N6O4 |
| Molecular Weight | 418.5 |
| Technology | Synthetic |
| Storage | -20°C, avoid light, cool and dry place |
| Application | Angiogenesis|Cancer Research|Cardiovascular System & Diseases|Di- and Tripeptides|Hematology|Inflammation Research |
| Description | H-Phe-Pro-Arg-OH is a tripeptide analog of the thrombin-receptor-derived peptide SFLLR. In the chick chorioallantoic membrane system it inhibited angiogenesis and caused a complete reversal of the angiogenesis-promoting effect of the thrombin-receptor-activating tetradecapeptide (TRAP (1-14)). H-Phe-Pro-Arg-OH has potential applications in the nonthrombotic actions of thrombin, e.g. cancer and inflammation, where angiogenesis is thought to play a pivotal role. |