| CAS | 144940-98-7 |
| Sequence | H-Pro-Asn-Thr-Cys-Glu-Ile-Cys-Ala-Tyr-Ala-Ala-Cys-Thr-Gly-Cys-OH (Disulfide bonds between Cys4 and Cys12/Cys7 and Cys15) |
| Sequence Single | PNTCEICAYAACTGC |
| Molecular Formula | C60H90N16O22S4 |
| Molecular Weight | 1515.73 |
| Technology | Synthetic |
| Storage | -20°C, avoid light, cool and dry place |
| Application | Gastrointestinal Research |
| Description | Guanylin activates the guanylate cyclase in the intestine to stimulate the production of cGMP, which in turn causes a secretory diarrhoea. Therefore, this peptide may play a role in regulating fluid and electrolyte absorption in intestines. |
| References | 1. Guanylin and related peptides. J.Beltowski, J. Physiol. Pharmacol., 52, 351 (2001) |