| CAS | 251634-22-7 |
| Sequence | Myr-Gln-Val-Pro-Ser-Arg-Pro-Asn-Arg-Ala-Pro-NH2 |
| Sequence Single | Myr-Gln-VPSRPNRAP-NH2 |
| Molecular Formula | C61H107N19O14 |
| Molecular Weight | 1330.64 |
| Technology | Synthetic |
| Storage | -20°C, avoid light, cool and dry place |
| Description | Dynamin inhibitory peptide, myristoylated is a cell-permeable version of dynamin inhibitory peptide, an inhibitor of the GTPase dynamin that competitively blocks binding of dynamin to amphiphysin, preventing endocytosis. Dynamin inhibitory peptide, myristoylated reduces NMDA receptor internalization. |
| References | 1. The SH3 domain of amphiphysin binds the proline-rich domain of dynamin at a single site that defines a new SH3 binding consensus sequence. Grabs et al (1997). J.Biol.Chem. 272 13419 PMID: 9148966 2. Constitutive endocytosis of GABAA receptors by an association with the adaptin AP2 complex modulates inhibitory synaptic currents in hippocampal neurons. Kittler et al (2000). J.Neurosci. 20 7972 PMID: 11050117 3. Glycine binding primes NMDA receptor internalization. Nong et al (2003). Nature 422 302 PMID: 12646920 |
Dynamin inhibitory peptide, myristoylated
CAS No.: 251634-22-7
Dynamin inhibitory peptide, myristoylated is a cell-permeable version of dynamin inhibitory peptide, an inhibitor of the
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